PUTTING THE HEALTH BACK IN HEALTHCARE
Medicine Redefined
Medicine Redefined
Dr. Darsh Shah, DO & Dr. Altamash Raja, DO interview practitioners who challenge the norm and promote health during a time when the healthcare system feels broken. Find out how experts in the fields of sleep, nutrition, exercise, stress resilience, rehabilitation, precision & performance medicine, and so many more are using "unconventional" approaches to move the needle forward and redefine medicine as we know it.
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207. Treatment-Resistant Depression: TMS, Ketamine, Spravato, and What Comes Next | Patrick Sullivan, DO

EPISODE DESCRIPTION If antidepressants haven't worked, is that the end of the road? Dr. Patrick "Rocky" Sullivan returns to break down transcranial magnetic stimulation — what it actually does to the brain, how it differs from ECT, and where it fits alongside ketamine and Spravato. He covers accelerated theta burst protocols, why insurance decides your session count, the gap between response and remission, and what clinics are overselling. Treatment-resistant, he argues, doesn't mean untreatable

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207. Treatment-Resistant Depression: TMS, Ketamine, Spravato, and What Comes Next | Patrick Sullivan, DO
Aug. 17, 2026

207. Treatment-Resistant Depression: TMS, Ketamine, Spravato, and What Comes Next | Patrick Sullivan, DO

EPISODE DESCRIPTION If antidepressants haven't worked, is that the end of the road? Dr. Patrick "Rocky" Sullivan returns to break down transcranial magnetic stimulation — what it actually does to the brain, how it differs from ECT, and where it fits alongside ketamine and Spravato. He covers accelerated theta burst protocols, why insurance decides your session count, the gap between response and remission, and what clinics are overselling. Treatment-resistant, he argues, doesn't mean untreatable
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206. FDA Approval on Peptides, Creating a Second Brain with AI, Red Light Therapy, and Building Capacity
Aug. 3, 2026

206. FDA Approval on Peptides, Creating a Second Brain with AI, Red Light Therapy, and Building Capacity

Dr. Darsh Shah and Dr. Altamash Raja catch up on hybrid athlete training, peptides, AI, red light therapy, health tech, and the balance between optimization and resilience. From HYROX prep and the rise of competitions like the Lifetime Games to recent peptide committee votes, CMS reimbursement cuts, and AI tools like Claude and ChatGPT, the conversation explores how new trends are changing fitness, medicine, and daily decision-making for both patients and doctors. They also reflect on building
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205. Beyond Rest and Recovery: What Actually Heals the Brain After Concussion | Marissa McCarthy, MD
July 20, 2026

205. Beyond Rest and Recovery: What Actually Heals the Brain After Concussion | Marissa McCarthy, MD

Dr. Darsh Shah and Dr. Altamash Raja sit down with Dr. Marissa McCarthy, a board-certified physical medicine and rehabilitation physician, brain injury specialist, and residency program director for the University of South Florida PM&R program. Dr. McCarthy practices at the USF Concussion Center and the Performance Lab in Tampa, where she works with athletes, military veterans, and patients recovering from traumatic brain injury. This conversation goes far beyond the basics of concussion care.
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Metabolic Flexibility Explained: Why Ketones May Be an Overlooked Health Marker | Dorian Greenow
July 6, 2026

Metabolic Flexibility Explained: Why Ketones May Be an Overlooked Health Marker | Dorian Greenow

Dr. Darsh Shah and Dr. Altamash Raja sit down with Dorian Greenow, founder of Keto-Mojo, for a wide-ranging conversation on ketosis, metabolic flexibility, chronic disease, and what it means to make health measurable. Dorian shares how his own experience with weight gain, depression, and discovering nutritional ketosis shaped the creation of Keto-Mojo. From the history of ketogenic diets to the difference between nutritional and therapeutic ketosis, the conversation explores food addiction, ket
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203. What Medical School Doesn’t Teach About Health, Fulfillment, and Finding Your Why | Brian Devorkin
June 22, 2026

203. What Medical School Doesn’t Teach About Health, Fulfillment, and Finding Your Why | Brian Devorkin

Dr. Darsh Shah and Dr. Altamash Raja sit down with Brian Devorkin, a third-year medical student at Case Western and host of BackedBriScience, for a wide-ranging conversation on fulfillment, longevity, chronic illness, and the harder questions behind choosing medicine. Brian shares how chronic fatigue and Lyme disease shaped his understanding of health, agency, and what it means to “get your life back.” From his gap year working with longevity researcher David Sinclair to the realities of medica
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202. Metabolic Osteoarthritis: How Fat Tissue Talks to Your Joints
June 8, 2026

202. Metabolic Osteoarthritis: How Fat Tissue Talks to Your Joints

In this episode, Dr. Darsh Shah and Dr. Altamash Raja explore the emerging concept of metabolic osteoarthritis and the growing evidence linking joint degeneration to obesity, insulin resistance, inflammation, and metabolic syndrome. They break down novel research on GLP-1 medications and metformin, discuss how excess adipose tissue may contribute to joint damage, and explain why treating metabolic health could become an important part of osteoarthritis care in the future. TOPICS COVERED • Is ost
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Reviews

Dynamic Doctor Duo

"This dynamic doctor duo makes my heart sing! They are incredibly forward thinking with their focus on “putting the health back in healthcare”, so insightful way beyond their years. I enjoy learning p…"

Robyn Tiger MD | Feb. 11, 2022

10/10 would recommend!

"Amazing podcast and interviewers! I especially love the wide variety of topics and guests, the flow of the conversation, the “lessons learned” series, and the last question “how do we put the health …"

Sarah AP | Aug. 4, 2022
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